Ever wondered if Bovril, that comforting staple in your kitchen, is actually good for your health? It’s a question many of us ask while enjoying this...
Losing weight can be a challenging process, but creating a sustainable plan focused on lifestyle changes rather than short-term fixes can set you up for long-term...
Background
Melatonin is commonly used to treat sleep disturbance in children and adolescents, although uncertainties about its optimal use remain.
ObjectiveTo determine to what extent prescribing of melatonin complies with evidence-based clinical practice standards.
MethodsAs part of a quality improvement programme, the...
Question
Tricyclic antidepressants are used to treat depression worldwide, but the adverse effects have not been systematically assessed. Our objective was to assess the beneficial and harmful effects of all tricyclic antidepressants for adults with major depressive disorder.
Study selection and...Background
Genetic and environmental factors contribute to the pathogenesis of schizophrenia (SZ) and bipolar disorder (BD). Among genetic risk groups stratified by combinations of Polygenic Risk Score (PRS) deciles for SZ, BD and SZ versus BD, genetic SZ risk groups...
Krave is trying to come across as something that is good for you. It’s packed with B vitamins and iron and doesn’t have any artificial colours...
Background
Internet-based cognitive–behavioural therapy (iCBT) is effective for subthreshold depression. However, iCBT has problems with adherence, especially when unaccompanied by human guidance. Knowledge on how to enhance adherence to iCBT without human involvement can contribute to improving the effectiveness of...
Background
Approximately 30% of patients experience substantial improvement in depression after 2 months without treatment, and 45% with antidepressants. The smallest worthwhile difference (SWD) refers to an intervention's smallest beneficial effect over a comparison patients deem worthwhile given treatment burdens...
In recent years, there has been a surge in interest surrounding CBD (cannabidiol) and its potential health benefits. One of the most popular and convenient ways...