Archive for Month: March

Decline in striatal binding ratio associated with accelerated decline in performance on symbol digit modality but not MoCA in Parkinson’s Disease Psychosis

Background

Cognitive deficits and reduced dopamine transporter (DAT) binding ratio have been reported in Parkinson's disease psychosis (PDP). However, it remains unclear whether DAT striatal binding ratio (SBR) may contribute to worsening cognitive performance in PDP.

Objectives

We examined this using data...

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Effect of the LifeSpan suicide prevention model on self-harm and suicide in four communities in New South Wales, Australia: a stepped-wedge, cluster randomised controlled trial

Background

There have been few rigorous evaluations of population, multi-strategy, suicide prevention programmes, despite increasing global recognition that such approaches are needed to reduce suicide.

Objective

To examine the effects of a multi-strategy suicide prevention model on age-standardised rates of hospital presenting...

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Prevalence and predictors of healthcare use for psychiatric disorders at 9 years after a first episode of psychosis: a Swedish national cohort study

Background

Psychotic disorders are known to exhibit heterogeneity with regards to illness course and prognosis, yet few studies have examined long-term healthcare use.

Objective

To determine the prevalence and predictors of healthcare use for psychiatric disorders at 9 years after the first...

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Capacity-building strategy for next-generation mental health research: embedding a national network infrastructure to grow mental health researcher capabilities and mental health lived-experience research leaders

Internationally, capacity building for mental health implementation and translation research has lagged. A review of literature found initiatives since 2008 indicating limited dedicated attention to growing capabilities of early-to-mid-career mental health researchers, and little reporting of tailored career pathways...

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Systematic review with qualitative meta-synthesis of parents’ experiences and needs in relation to having a child or young person with a mental health difficulty

Question

What are the experiences and needs of parents of children and young people (CYP) aged 5–18 with diagnosed mental health difficulties, particularly in relation to the parents' own well-being?

Study selection and analysis

A systematic review with thematic meta-synthesis was conducted,...

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Psychiatric morbidity in people with autoimmune arthritides as a model of inflammatory mechanisms in mental disorders

Background

Rheumatoid arthritis (RA) and axial spondyloarthritis (axSpA) are autoimmune illnesses characterised by chronic inflammation demonstrating differential associations with psychiatric conditions.

Objective

In this matched-cohort study, we aimed to investigate whether the associations between these inflammatory illnesses and mental disorders are predominantly...

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