Archive for Year: 2025

Guidelines and practice on antipsychotics prescribing and physical health monitoring in children and young people: a cohort study using primary care data

Background

Antipsychotic treatments require physical health monitoring (PHM), especially among children and young people (CYP).

Objective

For CYP aged 5-17, to investigate recorded indications for antipsychotics prescribing and first-treatment durations, and, for psychosis, bipolar disorder, autism spectrum disorder (ASD) and Tourette's syndrome,...

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Universal, selective and indicated parenting interventions to prevent the development of adverse mental health outcomes in youth: a meta-review of systematic reviews

Background

Preventive interventions in the form of parenting support can reduce the risk of mental disorders in children. Summarising the effectiveness of parenting interventions across different levels of prevention can inform the prioritisation of the intervention.

Objectives

We conducted a meta-review of...

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Use of GLP-1 receptor agonists and risks of suicide attempts or self-harm in patients with type 2 diabetes: a multicountry self-control case series study

Background

Inconclusive findings regarding the association between suicidal ideation/suicide attempt and glucagon-like peptide-1 receptor agonists (GLP-1RAs) have been recently revealed in a small number of studies.

Methods

This was a multinational self-controlled case series analysis using Hong Kong's Clinical Data Analysis and...

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