Systematic reviews and meta-analyses have become crucial for evidence-based decision-making in recent decades. However, it is common for the results of multiple reviews on the same topic to be inconsistent, and it is widely recognised that the results of...
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Background
The link between cardiometabolic disease and mental illness has been well established but remains incompletely explained. One hypothesis suggests that circadian rhythm dysregulation links cardiometabolic disease and mental illnesses. BMAL1 is a circadian rhythm regulatory gene. Human genetic studies...
Question
Collective evidence for the bidirectional association between depression and autoimmune diseases (ADs) is scarce, especially for subgroups of patients with specific ADs. We conducted a meta-analysis to determine the incidence rates and relative risks (RRs) of depression among patients...
Objective
This paper investigates how state-of-the-art generative artificial intelligence (AI) image models represent common psychiatric diagnoses. We offer key lessons derived from these representations to inform clinicians, researchers, generative AI companies, policymakers and the public about the potential impacts of...
Background
A persecutory delusion (severe paranoia) occurs when a person believes that others are trying to harm them when they are not. It is often a central difficulty for patients diagnosed with schizophrenia.
ObjectiveThe objective is to identify potentially important research...
Let’s be honest—when it comes to building strong, sculpted glutes, squats are the first exercise that comes to mind. They’re a classic for a reason, hitting...
Introduction
Advancing research and support for neurologically diverse populations requires novel data harmonisation methods that are capable of aligning with contemporary approaches to understanding health and disability.
ObjectivesWe present the International Classification of Functioning, Disability and Health (ICF) as a conceptual...
Ever notice how much harder life feels after a bad night’s sleep? You’re not imagining it—sleep and mental health are more connected than most people realize....
Background
Research has revealed associations between microbes of the gastrointestinal tract and stress, anxiety and depression in pregnant or postpartum women. While these studies suggest a gut-brain-behaviour axis, no studies have examined microbes of the oral cavity in relation to...
Question
The optimal dose of lurasidone for bipolar depression is unclear. This study examined its dose–response relationship for efficacy, acceptability, and metabolic/endocrine profiles.
Study selection and analysisFive databases and grey literature published until 1 August 2024, were systematically reviewed. The outcomes...