Background
Alzheimer's disease (AD), type 2 diabetes mellitus (characterised by insulin resistance) and depression are significant challenges facing public health. Research has demonstrated common comorbidities...
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Background
Digital phenotyping methods present a scalable tool to realise the potential of personalised medicine. But underlying this potential is the need for digital phenotyping...
In recent years, network meta-analyses have been increasingly carried out to inform clinical guidelines and policy. This approach is under constant development, and a...
Digital innovations in mental health offer great potential, but present unique challenges. Using a consensus development panel approach, an expert, international, cross-disciplinary panel met...
Question
Randomised controlled trials assessing treatments for anxiety, obsessive-compulsive and stress-related disorders often present high placebo response rates in placebo groups. Understanding the placebo response...
Background
Blinding of randomised controlled trials (RCTs) is very important for the accurate assessment of drug efficacy. Without proper blinding, the effect of the...