Question
Are antipsychotic dose equivalents between acute mania and schizophrenia the same?
Study selection and analysisSix databases were systematically searched (from inception to 17 September 2022) to identify blinded randomised controlled trials (RCTs) that used a flexible-dose oral antipsychotic drug for...
Background
Dementia incidence is increasing across the globe and currently there are no disease-modifying pharmaceutical treatments. The Lancet Commission on dementia identified 12 modifiable risk factors which explain 40% of dementia incidence. However, whether these associations are causal in nature...
Anxiety is the anticipation of a future real or perceived threat and is often associated with “muscle tension and vigilance in preparation for future danger and cautious or avoidant behaviors.” Symptoms may include excessive anxiety, palpitations, restlessness, fatigue, trembling,...
Background
Suicide prevention remains a high priority topic across government and the National Health Service (NHS). Prevention of Future Death (PFD) reports are produced by coroners to highlight concerns that should be addressed by organisations to prevent future deaths in...