Background
The Children’s Yale-Brown Obsessive-Compulsive Scale (CYBOCS) is a clinician rated instrument developed to quantify severity of obsessive-compulsive disorder (OCD) in children and adolescents.1 Although the CYBOCS is the gold standard for outcome in clinical research and practice, the minimal required symptom reduction that constitutes the threshold for clinical improvement is unknown. One way of defining the ‘minimal important difference’ (MID) is by comparing the CYBOCS with the Clinical Global Impression-Improvement (CGI-I) scale, where a CGI of 3 (‘minimally improved’) is used as the MID. Equipercentile linking can be employed to establish corresponding outcomes between the CYBOCS and the CGI-I scale. The method has been used to link CGI with psychometric scales of major depressive disorder (MDD), anxiety, bipolar disorder and schizophrenia.2 In this study, we linked the CYBOCS to the CGI-I in order to find the MID for paediatric OCD.
Study…
