Background
Metformin is a pharmacological candidate to mitigate second-generation antipsychotic (SGA)-induced weight gain in patients diagnosed with severe mental illnesses (SMI).
ObjectiveTo determine the incidence, prevalence and demographic patterns of metformin co-prescription among patients diagnosed with SMI initiating SGAs. To estimate...
Background
Cognitive deficits and reduced dopamine transporter (DAT) binding ratio have been reported in Parkinson's disease psychosis (PDP). However, it remains unclear whether DAT striatal binding ratio (SBR) may contribute to worsening cognitive performance in PDP.
ObjectivesWe examined this using data...
Background
There have been few rigorous evaluations of population, multi-strategy, suicide prevention programmes, despite increasing global recognition that such approaches are needed to reduce suicide.
ObjectiveTo examine the effects of a multi-strategy suicide prevention model on age-standardised rates of hospital presenting...
It’s pretty amazing how much nature offers us when it comes to healing and feeling better — whether that’s through natural remedies, time spent outside, or...
Background
The Hamilton Rating Scale for Depression (HRSD) and the Montgomery-Åsberg Depression Rating Scale (MADRS) are the two most common clinician-rated scales to quantify depression symptom change in repetitive transcranial magnetic stimulation (rTMS) trials. However, it is unclear how the...
Question
Mental health complaints are increased in survivors of natural hazards and disaster responders. This meta-analysis assessed the efficacy of psychological and psychosocial interventions for the prevention of mental disorders after exposure to natural hazards.
Study selection and analysisWe searched Web...
Background
Psychotic disorders are known to exhibit heterogeneity with regards to illness course and prognosis, yet few studies have examined long-term healthcare use.
ObjectiveTo determine the prevalence and predictors of healthcare use for psychiatric disorders at 9 years after the first...
Internationally, capacity building for mental health implementation and translation research has lagged. A review of literature found initiatives since 2008 indicating limited dedicated attention to growing capabilities of early-to-mid-career mental health researchers, and little reporting of tailored career pathways...
Question
What are the experiences and needs of parents of children and young people (CYP) aged 5–18 with diagnosed mental health difficulties, particularly in relation to the parents' own well-being?
Study selection and analysisA systematic review with thematic meta-synthesis was conducted,...
Background
Rheumatoid arthritis (RA) and axial spondyloarthritis (axSpA) are autoimmune illnesses characterised by chronic inflammation demonstrating differential associations with psychiatric conditions.
ObjectiveIn this matched-cohort study, we aimed to investigate whether the associations between these inflammatory illnesses and mental disorders are predominantly...