Effectiveness of pharmacological and non-pharmacological interventions for treatment-resistant depression in older patients: a systematic review and meta-analysis

2 years ago

Background Depression in older adults is often undertreated. A 2011 systematic review of treatments for treatment-resistant depression (TRD) in older…

Chronotherapeutic considerations of benzodiazepine administration for agitation management in the emergency department

2 years ago

Objective Agitation in the emergency department (ED) affects up to 2.6% of encounters, posing significant risks to patients and caregivers.…

Lack of neuropsychological effects following short-term subcallosal cingulate gyrus deep brain stimulation in treatment-resistant depression: a randomised crossover study

2 years ago

Background The subcallosal cingulate gyrus (SCG) is integral to cognitive function and mood regulation. Open-label SCG deep brain stimulation (DBS)…

Advancing mixed methods in mental health research

2 years ago

In the mental health research field, there is a need for effective and robust methodological approaches that are able to…

Bridging assessment and treatment for repeat suicidality in prisons: development and validation of a risk model

2 years ago

Background Suicidal thoughts and behaviours are common in people in prison and associated with poor health outcomes, including suicide, injury…

How Much Protein Is in Avocado Toast? (And Easy Ways to Boost It!)

2 years ago

I love a good avocado toast—simple, delicious, and healthy. But until recently, I had no idea it actually contains a…

Chronotherapeutic intervention targeting emotion regulation brain circuitry, symptoms, and suicide risk in adolescents and young adults with bipolar disorder: a pilot randomised trial

2 years ago

Background Mood episodes and high suicide risk of bipolar disorder (BD) are thought to derive from amygdala–ventral prefrontal cortex emotion…

How to Prevent Tennis Elbow (and Recover Faster If You Already Have It!)

2 years ago

Tennis elbow isn’t just a problem for tennis players—it can affect anyone who grips, lifts, or moves their arm repetitively.…

Digital sleep phenotype and wrist actigraphy in individuals at clinical high risk for psychosis and people with schizophrenia spectrum disorders: a systematic review and meta-analysis

2 years ago

Aim To identify sleep abnormalities in individuals at clinical high risk for psychosis (CHR-P) or with schizophrenia spectrum disorders (SSDs)…

Professional experiences on use of the mental health act in ethnically diverse populations: a photovoice study

2 years ago

Background There are long-standing ethnic and racial inequalities in experiences and outcomes of severe mental illness, including compulsory admission and…