Efficacy and acceptability of lurasidone for bipolar depression: a systematic review and dose-response meta-analysis

2 years ago

Question The optimal dose of lurasidone for bipolar depression is unclear. This study examined its dose–response relationship for efficacy, acceptability,…

Are Sardines in Tomato Sauce Good for You?

2 years ago

Sardines in tomato sauce are a classic cupboard staple—cheap, versatile, and easy to whip up into a quick meal. Whether…

Predictors of study dropout in cognitive-behavioural therapy with a trauma focus for post-traumatic stress disorder in adults: An individual participant data meta-analysis

2 years ago

Background Available empirical evidence on participant-level factors associated with dropout from psychotherapies for post-traumatic stress disorder (PTSD) is both limited…

Trans and gender diverse identities in adolescent health research: making the most of imperfect data

2 years ago

Advancing adolescent health research necessitates deliberate design and analysis that accurately captures the rapidly evolving world in which adolescents live…

Integrating early life stress in neurological disease: advancing preventive neurology

2 years ago

Background In 2021, an estimated 43% of the world's population had been diagnosed with a neurological disorder. Early life stress…

Healthcare utilisation and costs associated with poor access to diagnosis and treatment for children and young people with tic disorders

2 years ago

Background There are no specific national guidelines in England to guide healthcare professionals in how to assess or treat young…

Cost-effectiveness of psychological and psychosocial interventions for adults, children and young people who have self-harmed

2 years ago

Background Self-harm is a major health issue resulting in high societal costs. Few psychological and psychosocial interventions have shown effectiveness…

Thinking of Wearing Crocs to the Gym? Here’s Why You Should Think Again

2 years ago

Is there anybody who doesn’t love Crocs? They’re comfy, easy to slip on, and kind of iconic, aren’t they? I’ll…

Basic self-disturbance in adolescents at risk of psychosis: temporal stability investigated by the experience sampling method in a mixed method study

2 years ago

Background Basic self-disturbance (BSD), also called anomalous self-experiences (ASEs), are core phenotypic markers for schizophrenia spectrum disorders and a prepsychotic…

Association between cannabis use and brain structure and function: an observational and Mendelian randomisation study

2 years ago

Background Cannabis use during adolescence and young adulthood has been associated with brain harm, yet despite a rapid increase in…