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Positive affect training to reduce mental health problems during the COVID-19 pandemic: a proof-of-concept randomised clinical trial

Background The social restrictions occurring during the pandemic contributed to loss of many sources of reward, which contributes to poor…

3 years ago

Physical injuries as triggers for self-harm: a within-individual study of nearly 250 000 injured people with a major psychiatric disorder

Background Although there is robust evidence for several factors which may precipitate self-harm, the contributions of different physical injuries are…

3 years ago

Population health surveys and screening tools for depressive disorders: aims and uses

The article by Fischer and colleagues,1 based on data from the second wave of the European Health Interview Survey (EHIS-2),…

3 years ago

Predicting outcomes at the individual patient level: what is the best method?

Objective When developing prediction models, researchers commonly employ a single model which uses all the available data (end-to-end approach). Alternatively,…

3 years ago

Assessing violence risk in first-episode psychosis: external validation, updating and net benefit of a prediction tool (OxMIV)

Background Violence perpetration is a key outcome to prevent for an important subgroup of individuals presenting to mental health services,…

3 years ago

New living evidence resource of human and non-human studies for early intervention and research prioritisation in anxiety, depression and psychosis

In anxiety, depression and psychosis, there has been frustratingly slow progress in developing novel therapies that make a substantial difference…

3 years ago

Associations between antipsychotics and the risk of incident cardiovascular diseases in individuals with schizophrenia: a nested case-control study

Background The association between antipsychotics and cardiovascular diseases (CVDs) remains significant yet unestablished, especially in Chinese populations. Objective To investigate…

3 years ago

Effectiveness of a mental health stepped-care programme for healthcare workers with psychological distress in crisis settings: a multicentre randomised controlled trial

Background Evidence-based mental health interventions to support healthcare workers (HCWs) in crisis settings are scarce. Objective To evaluate the capacity…

3 years ago

Insulin resistance, age and depressions impact on cognition in middle-aged adults from the PREVENT cohort

Background Alzheimer's disease (AD), type 2 diabetes mellitus (characterised by insulin resistance) and depression are significant challenges facing public health.…

3 years ago

Increasing the value of digital phenotyping through reducing missingness: a retrospective review and analysis of prior studies

Background Digital phenotyping methods present a scalable tool to realise the potential of personalised medicine. But underlying this potential is…

3 years ago