Background
Psychiatric disorders alone are associated with an increased risk of developing dementia. However, the relationship between co-occurring psychiatric disorders and dementia odds remains unclear. This study aimed to assess the odds of dementia (all types) among individuals with several...
Background
Electrodermal activity (EDA) is a measure of sympathetic arousal that has been linked to depression in laboratory experiments. However, the inability to measure EDA passively over time and in the real world has limited conclusions that can be drawn...
Background
Mental health conditions arising from work are a rapidly increasing burden for individuals, employers and society, and are challenging to diagnose and treat.
ObjectiveTo assess the effectiveness of a multicomponent intervention on increasing general practitioners' (GPs') adherence to the ‘Clinical...
Question
What are the values and preferences of safer opioid supply clients?
Study selection and analysisWe conducted a systematic review of qualitative studies on safer opioid supply client experiences published between January 2016 and August 2024. Searches were conducted across seven...
Background
The lack of an early warning score for psychiatric hospitalisation means that the decision to initiate preventative interventions is based solely on clinical judgement, which is prone to bias.
ObjectiveThe objective is to develop and externally validate a transdiagnostic score...
Background
Individuals with attention deficit hyperactivity disorder (ADHD) are at a higher risk of depression and lower quality of life (QoL); however, it is unclear whether disrupted sleep and circadian rhythms mediate this increased risk.
ObjectivesWe investigated whether disruption of self-reported...
Background
Antipsychotic treatments require physical health monitoring (PHM), especially among children and young people (CYP).
ObjectiveFor CYP aged 5-17, to investigate recorded indications for antipsychotics prescribing and first-treatment durations, and, for psychosis, bipolar disorder, autism spectrum disorder (ASD) and Tourette's syndrome,...
Background
Premenstrual disorders (PMDs) are prevalent and impair women's quality of life, but their long-term influence on work capacity is unclear. Understanding the association between PMDs and subsequent sick leave and unemployment could inform interventions and policies.
ObjectiveWe hypothesised that women...
Background
Timely access to diagnostic assessment and treatment is essential to improve function and mitigate the risk of poor long-term outcomes in children and young people (CYP) with tics.
ObjectiveThis study aimed to explore (i) how tic services for CYP in...
Background
Preventive interventions in the form of parenting support can reduce the risk of mental disorders in children. Summarising the effectiveness of parenting interventions across different levels of prevention can inform the prioritisation of the intervention.
ObjectivesWe conducted a meta-review of...