Mental health

Cause-specific excess mortality after first diagnosis of bipolar disorder: population-based cohort study

Background Bipolar disorder (BD) is associated with increased mortality, but evidence on cause-specific mortality is limited. Objective To investigate cause-specific…

2 years ago

Patients requesting and receiving euthanasia for psychiatric disorders in the Netherlands

Background Euthanasia and assisted suicide (EAS) for patients with psychiatric disorders occupies a prominent place in the public debate, but…

2 years ago

Risk of death by suicide following self-harm presentations to healthcare: development and validation of a multivariable clinical prediction rule (OxSATS)

Background Assessment of suicide risk in individuals who have self-harmed is common in emergency departments, but is often based on…

2 years ago

Positive affect training to reduce mental health problems during the COVID-19 pandemic: a proof-of-concept randomised clinical trial

Background The social restrictions occurring during the pandemic contributed to loss of many sources of reward, which contributes to poor…

2 years ago

Physical injuries as triggers for self-harm: a within-individual study of nearly 250 000 injured people with a major psychiatric disorder

Background Although there is robust evidence for several factors which may precipitate self-harm, the contributions of different physical injuries are…

2 years ago

Population health surveys and screening tools for depressive disorders: aims and uses

The article by Fischer and colleagues,1 based on data from the second wave of the European Health Interview Survey (EHIS-2),…

2 years ago

Assessing violence risk in first-episode psychosis: external validation, updating and net benefit of a prediction tool (OxMIV)

Background Violence perpetration is a key outcome to prevent for an important subgroup of individuals presenting to mental health services,…

2 years ago

Predicting outcomes at the individual patient level: what is the best method?

Objective When developing prediction models, researchers commonly employ a single model which uses all the available data (end-to-end approach). Alternatively,…

2 years ago

Associations between antipsychotics and the risk of incident cardiovascular diseases in individuals with schizophrenia: a nested case-control study

Background The association between antipsychotics and cardiovascular diseases (CVDs) remains significant yet unestablished, especially in Chinese populations. Objective To investigate…

2 years ago

New living evidence resource of human and non-human studies for early intervention and research prioritisation in anxiety, depression and psychosis

In anxiety, depression and psychosis, there has been frustratingly slow progress in developing novel therapies that make a substantial difference…

2 years ago