Mental health

Components of cognitive-behavioural therapy for mitigating core symptoms in attention-deficit hyperactivity disorder: a systematic review and network meta-analys

Question Cognitive–behavioural therapy (CBT) is frequently implemented for individuals with attention-deficit hyperactivity disorder (ADHD). It is still unknown which specific…

1 month ago

Data sharing in circadian rhythm and mental health research: current status, challenges, recommendations and future directions.

Data sharing is a cornerstone of modern scientific research, playing a critical role in fostering greater collaboration, enhancing reproducibility, transparency…

1 month ago

Umbrella-Review, Evaluation, Analysis and Communication Hub (U-REACH): a novel living umbrella review knowledge translation approach

Systematic reviews and meta-analyses have become crucial for evidence-based decision-making in recent decades. However, it is common for the results…

1 month ago

Genetic variation in circadian regulator gene BMAL1 in psychiatric, psychological and cardiometabolic traits: a trans-ancestry UK Biobank study

Background The link between cardiometabolic disease and mental illness has been well established but remains incompletely explained. One hypothesis suggests…

2 months ago

Elucidating the bidirectional association between autoimmune diseases and depression: a systematic review and meta-analysis

Question Collective evidence for the bidirectional association between depression and autoimmune diseases (ADs) is scarce, especially for subgroups of patients…

2 months ago

AI depictions of psychiatric diagnoses: a preliminary study of generative image outputs in Midjourney V.6 and DALL-E 3

Objective This paper investigates how state-of-the-art generative artificial intelligence (AI) image models represent common psychiatric diagnoses. We offer key lessons…

2 months ago

Potential research priorities for understanding and treating severe paranoia (persecutory delusions): a priority-setting partnership between patients, carers, mental health staff, and researchers

Background A persecutory delusion (severe paranoia) occurs when a person believes that others are trying to harm them when they…

2 months ago

Conceptual framework for data harmonisation in mental health using the International Classification of Functioning, Disability and Health: an example with the R2D2-MH consortium

Introduction Advancing research and support for neurologically diverse populations requires novel data harmonisation methods that are capable of aligning with…

2 months ago

Stress and mental health symptoms in early pregnancy are associated with the oral microbiome

Background Research has revealed associations between microbes of the gastrointestinal tract and stress, anxiety and depression in pregnant or postpartum…

2 months ago

Efficacy and acceptability of lurasidone for bipolar depression: a systematic review and dose-response meta-analysis

Question The optimal dose of lurasidone for bipolar depression is unclear. This study examined its dose–response relationship for efficacy, acceptability,…

2 months ago