Mental health

Fractal biomarker of daily activity for women with early onset depression

Background Depression is a major health issue in adolescence and young adulthood, emphasising the need for early risk identification. Patients…

9 months ago

Multivariate brain morphological patterns across mood disorders: key roles of frontotemporal and cerebellar areas

Background Differentiating major depressive disorder (MDD) from bipolar disorder (BD) remains a significant clinical challenge, as both disorders exhibit overlapping…

9 months ago

Affective disorders and chronic inflammatory conditions: analysis of 1.5 million participants in Our Future Health

Background Chronic inflammation is associated with psychiatric disorders. If inflammation is linked mechanistically to mental health, people living with chronic…

9 months ago

Intimate partner violence, traumatic brain injury and long-term mental health outcomes in midlife: the Drake IPV study

Background Approximately 30% of women experience intimate partner violence (IPV) in their lifetime, often with traumatic brain injury (TBI) exposure.…

9 months ago

Self-harm incidence among children and young people 2019–2023: time series analysis of electronic health records in Greater Manchester, England

Background The mental health of children and adolescents has declined in recent years. Self-harm is frequently an expression of this…

9 months ago

Circadian rhythms and mental health

Well-synchronised circadian rhythms are fundamental for human health and particularly mental health, but patterns of modern living—including, for example, shift…

9 months ago

Association of a child’s mental disorder with parental income and employment: analysis of nationwide register-based cohorts in Finland and Denmark

Background The onset of a severe physical illness of a child has been associated with earnings and employment losses among…

9 months ago

Early Start Denver Model effectiveness in young autistic children: a large multicentric randomised controlled trial in two European countries

Background Evidence regarding early interventions based on the Naturalistic Developmental Behavioral Interventions framework, such as the Early Start Denver Model…

9 months ago

Risk of bias in routine mental health outcome data: the case of Health of the Nation Outcome Scales

Background Routine outcome data in secondary mental health services have significant potential for service planning, evaluation and research. Expanding the…

9 months ago

General disease factor: evidence of a unifying dimension across mental and physical illness in children and adolescents

Background Understanding the relationship between mental and physical health conditions is crucial for developing comprehensive healthcare strategies. The putative existence…

9 months ago