Mental health

Chronotherapeutic intervention targeting emotion regulation brain circuitry, symptoms, and suicide risk in adolescents and young adults with bipolar disorder: a pilot randomised trial

Background Mood episodes and high suicide risk of bipolar disorder (BD) are thought to derive from amygdala–ventral prefrontal cortex emotion…

2 months ago

Digital sleep phenotype and wrist actigraphy in individuals at clinical high risk for psychosis and people with schizophrenia spectrum disorders: a systematic review and meta-analysis

Aim To identify sleep abnormalities in individuals at clinical high risk for psychosis (CHR-P) or with schizophrenia spectrum disorders (SSDs)…

3 months ago

Professional experiences on use of the mental health act in ethnically diverse populations: a photovoice study

Background There are long-standing ethnic and racial inequalities in experiences and outcomes of severe mental illness, including compulsory admission and…

3 months ago

Will things feel better in the morning? A time-of-day analysis of mental health and wellbeing from nearly 1 million observations

Background Mood is known to change over seasons of the year, days of the week, and even over the course…

3 months ago

A qualitative study exploring the feasibility and acceptability of computerised adaptive testing to assess and monitor children and young peoples mental health in primary care settings in the UK

Background The increasing prevalence of mental health disorders among adolescents highlights the importance of early identification and intervention. Artemis-A is…

3 months ago

Minimally important change on the Columbia Impairment Scale and Strengths and Difficulties Questionnaire in youths seeking mental healthcare

Background Evidence-based mental health requires patient-relevant outcome data, but many indicators lack clinical meaning and fail to consider youth perceptions.…

3 months ago

Comparing apples and oranges in youth depression treatments? A quantitative critique of the evidence base and guidelines

Objectives Should a young person receive psychotherapy or medication for their depression and on what evidence do we base this…

3 months ago

Cost-utility of behavioural activation for mitigating psychological impacts of COVID-19 on socially isolated older adults with depression and multiple long-term conditions compared with usual care: results from a pragmatic randomised controlled trial

Background Depression alongside multiple long-term conditions (MLTCs) in older adults poses a critical public health challenge, worsening physical and mental…

3 months ago

Multigenerational family coaggregation study of obsessive-compulsive disorder and cardiometabolic disorders

Background Obsessive-compulsive disorder (OCD) is associated with an increased risk of morbidity and mortality due to cardiometabolic disorders. Whether this…

3 months ago

Prognostic models for depression and post-traumatic stress disorder symptoms following traumatic brain injury: a CENTER-TBI study

Background Traumatic brain injury (TBI) is associated with an increased risk of major depressive disorder (MDD) and post-traumatic stress disorder…

3 months ago