Mental health

Elucidating the bidirectional association between autoimmune diseases and depression: a systematic review and meta-analysis

Question Collective evidence for the bidirectional association between depression and autoimmune diseases (ADs) is scarce, especially for subgroups of patients…

5 months ago

AI depictions of psychiatric diagnoses: a preliminary study of generative image outputs in Midjourney V.6 and DALL-E 3

Objective This paper investigates how state-of-the-art generative artificial intelligence (AI) image models represent common psychiatric diagnoses. We offer key lessons…

5 months ago

Potential research priorities for understanding and treating severe paranoia (persecutory delusions): a priority-setting partnership between patients, carers, mental health staff, and researchers

Background A persecutory delusion (severe paranoia) occurs when a person believes that others are trying to harm them when they…

5 months ago

Conceptual framework for data harmonisation in mental health using the International Classification of Functioning, Disability and Health: an example with the R2D2-MH consortium

Introduction Advancing research and support for neurologically diverse populations requires novel data harmonisation methods that are capable of aligning with…

5 months ago

Stress and mental health symptoms in early pregnancy are associated with the oral microbiome

Background Research has revealed associations between microbes of the gastrointestinal tract and stress, anxiety and depression in pregnant or postpartum…

5 months ago

Efficacy and acceptability of lurasidone for bipolar depression: a systematic review and dose-response meta-analysis

Question The optimal dose of lurasidone for bipolar depression is unclear. This study examined its dose–response relationship for efficacy, acceptability,…

5 months ago

Predictors of study dropout in cognitive-behavioural therapy with a trauma focus for post-traumatic stress disorder in adults: An individual participant data meta-analysis

Background Available empirical evidence on participant-level factors associated with dropout from psychotherapies for post-traumatic stress disorder (PTSD) is both limited…

6 months ago

Trans and gender diverse identities in adolescent health research: making the most of imperfect data

Advancing adolescent health research necessitates deliberate design and analysis that accurately captures the rapidly evolving world in which adolescents live…

6 months ago

Healthcare utilisation and costs associated with poor access to diagnosis and treatment for children and young people with tic disorders

Background There are no specific national guidelines in England to guide healthcare professionals in how to assess or treat young…

6 months ago

Integrating early life stress in neurological disease: advancing preventive neurology

Background In 2021, an estimated 43% of the world's population had been diagnosed with a neurological disorder. Early life stress…

6 months ago