Mental health

Cost-effectiveness of psychological and psychosocial interventions for adults, children and young people who have self-harmed

Background Self-harm is a major health issue resulting in high societal costs. Few psychological and psychosocial interventions have shown effectiveness…

6 months ago

Basic self-disturbance in adolescents at risk of psychosis: temporal stability investigated by the experience sampling method in a mixed method study

Background Basic self-disturbance (BSD), also called anomalous self-experiences (ASEs), are core phenotypic markers for schizophrenia spectrum disorders and a prepsychotic…

6 months ago

Association between cannabis use and brain structure and function: an observational and Mendelian randomisation study

Background Cannabis use during adolescence and young adulthood has been associated with brain harm, yet despite a rapid increase in…

6 months ago

Development and validation of a prognostic model to predict relapse in adults with remitted depression in primary care: secondary analysis of pooled individual participant data from multiple studies

Background Relapse of depression is common and contributes to the overall associated morbidity and burden. We lack evidence-based tools to…

6 months ago

Association between severe childhood infections and subsequent risk of OCD is largely explained by shared familial factors

Introduction Obsessive-compulsive disorder (OCD) is only moderately heritable1 2, but surprisingly little is known about potential environmental risk factors contributing…

6 months ago

Randomised controlled trial comparing different intersession intervals of intermittent theta burst delivered to the dorsal medial prefrontal cortex

Background Intermittent theta burst stimulation (iTBS) is a form of repetitive transcranial magnetic stimulation (rTMS) that can be administered in…

6 months ago

Risk of repeat self-harm among individuals presenting to healthcare services: development and validation of a clinical risk assessment model (OxSET)

Background A self-harm episode is a major risk factor for repeat self-harm. Existing tools to assess and predict repeat self-harm…

6 months ago

Complex trauma and the unseen: who gets to be a victim?

The inclusion of complex post-traumatic stress disorder (cPTSD) in the International Classification of Diseases 11th Revision in January 2022 marks…

6 months ago

Systematic review of interventions for mental health, cognition and psychological well-being in long COVID

Aims This systematic review aims to identify and synthesise the publicly available research testing treatments for mental health, cognition and…

7 months ago

Changes in sleep patterns in people with a history of depression during the COVID-19 pandemic: a natural experiment

Background The COVID-19 pandemic, while a major stressor, increased flexibility in sleep–wake schedules. Objectives To investigate the impact of the…

7 months ago