Mental health

Understanding the protective effect of social support on depression symptomatology from a longitudinal network perspective

Background Higher social support protects people from developing mental disorders. Limited evidence is available on the mechanism through which social…

1 year ago

Socioeconomic status and severe mental disorders: a bidirectional multivariable Mendelian randomisation study

Background Despite the evidence supporting the relationship between socioeconomic status (SES) and severe mental disorders (SMD), the directionality of the…

1 year ago

Relationship between self-stigma about alcohol dependence and severity of alcohol drinking and craving

Background The correlates and consequences of stigma surrounding alcohol use are complex. Alcohol use disorder (AUD) is typically accompanied by…

1 year ago

Genetically predicted causal associations between periodontitis and psychiatric disorders

Background Psychiatric disorders have serious harm to individuals' lives with high disease burden. Observational studies reported inconsistent associations between periodontitis…

1 year ago

Comparative analysis of algorithm-guided treatment and predefined duration treatment programmes for depression: exploring cost-effectiveness using routine care data

Background More knowledge on the cost-effectiveness of various depression treatment programmes can promote efficient treatment allocation and improve the quality…

1 year ago

ChatGPT and mental healthcare: balancing benefits with risks of harms

Against the global need for increased access to mental services, health organisations are looking to technological advances to improve the…

1 year ago

Explaining paranoia: cognitive and social processes in the occurrence of extreme mistrust

Background Paranoia—incorrectly thinking that others are deliberating trying to harm you—causes distress, undermines social interactions and leads to withdrawal. It…

1 year ago

Seasonal trends in antidepressant prescribing, depression, anxiety and self-harm in adolescents and young adults: an open cohort study using English primary care data

Background There is an increasing demand for mental health services for young people, which may vary across the year. Objective…

1 year ago

Treatments for partial remission of major depressive disorder: a systematic review and meta-analysis

Question Partial remission of major depressive disorder (MDD) is a debilitating and distressing clinical state related to chronicity, morbidity and…

1 year ago

Early parenting interventions to prevent internalising problems in children and adolescents: a global systematic review and network meta-analysis

Question We compared the effectiveness of different types of parenting interventions based on an a priori taxonomy, and the impact…

1 year ago