Background
Increasing data suggest emergent affective symptoms during the COVID-19 pandemic.
ObjectivesTo study the impact of the COVID-19 pandemic on affective symptoms and suicidal ideation in Thai adults.
MethodsThe Collaborative Outcomes Study on Health and Functioning during Infection Times uses non-probability sampling...
Background
All-cause and suicide mortalities of gender-referred adolescents compared with matched controls have not been studied, and particularly the role of psychiatric morbidity in mortality is unknown.
ObjectiveTo examine all-cause and suicide mortalities in gender-referred adolescents and the impact of psychiatric...
Question
Depression is highly prevalent and associated with numerous adverse consequences for both individuals and society. Due to low uptake of direct treatment, interventions that target related, but less stigmatising problems, such as perceived stress, have emerged as a new...
Question
We examined the effect of study characteristics, risk of bias and publication bias on the efficacy of pharmacotherapy in randomised controlled trials (RCTs) for obsessive-compulsive disorder (OCD).
Study selection and analysisWe conducted a systematic search of double-blinded, placebo-controlled, short-term RCTs...
Background
The relationship between adverse childhood experiences (ACEs) and depression risk has been well documented. However, it remains unclear whether stress-related chronic conditions associated with ACEs, such as asthma, increase the long-term mental health burden of ACEs.
ObjectiveTo investigate the joint...
Background
Patients diagnosed with psychosis often spend less time than others engaged in exercise and more time sitting down, which likely contributes to poorer physical and mental health.
ObjectiveThe aim of this study was to develop a comprehensive framework from the...
Question
Children and young people experience delays in assessment and/or treatment within mental health services. The objective of this systematic review, funded by the Emerging Minds Network, was to explore the current evidence base for mental health waiting list interventions...
Background
Post-traumatic stress symptoms (PTSS) are frequently observed in those who have experienced trauma events like the COVID-19 outbreak. The cognitive model of PTSS highlights the relationship between PTSS and negative interpretation bias.
ObjectiveThe present study aimed to modify interpretation bias...
Question
Tricyclic antidepressants are used to treat depression worldwide, but the adverse effects have not been systematically assessed. Our objective was to assess the beneficial and harmful effects of all tricyclic antidepressants for adults with major depressive disorder.
Study selection and...Background
Melatonin is commonly used to treat sleep disturbance in children and adolescents, although uncertainties about its optimal use remain.
ObjectiveTo determine to what extent prescribing of melatonin complies with evidence-based clinical practice standards.
MethodsAs part of a quality improvement programme, the...